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Foot & Ankle Stem Cell and PRP Treatment and Therapy

Have you been told your only option for foot, ankle or heel pain is steroid injections or joint fusion surgery?

Minimally invasive regenerative alternatives offer pain relief and can help you get your lifestyle back on track

Foot and ankle injuries are common, particularly among sports enthusiasts. Many of these injuries can be treated with stem cell therapy, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) therapy.

When the ligaments which hold the bones of the ankle joint together are partially torn or stretched, for example when you badly sprain your ankle, they become painful, loose and weak. This changes how you walk and puts stress on other joints of the foot.

Ankle sprains and injuries which aren’t too severe can be treated with PRP therapy which will heal damaged tissues and tighten the loose ligaments.

According to Arthritis Research UK, 1 in 5 people who have sought treatment for osteoarthritis have it in their foot or ankle.

Arthritis is a condition which destroys the inner workings of your joints, including your ankles and any of the 30 joints in each foot. Osteoarthritis is the most common form and it slowly wears away joint cartilage and results from the wear and tear of old age.

Surgical treatment for common ankle injuries and arthritis include ankle arthroscopy, fusion of ankle bones and tendon grafts. These procedures can lead to a painful post-operative recovery.

Plantar fasciitis is one of the most common causes of heel pain and is often found in runners. It is caused by inflammation of a thick band of tissue which runs across the bottom of your foot and connects your heel bone to your toes. Plantar fasciitis causes stabbing pain which often occurs with your first steps in the morning.  It is usually treated with physiotherapy and corticosteroid injections.

All the conditions above can be treated with stem cell therapy, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) treatment. which offer a shorter recovery time and less risk than surgery. Following these procedures, patients are often encouraged to walk the same d

Foot and ankle conditions which can be treated with AMPP® and PRP therapy include:

Foot Pain

Ankle Pain

Heel Pain

Achilles Tendinopathy

Plantar Fasciitis


Peroneal Tendon Pain or Injury

Ligament Pain or Injury

Sub-talar Arthritis


The treatment

A pioneering new treatment using your body’s own stem cells to treat pain and inflammation. The minimally invasive procedure is a possible alternative to having an operation or can be used after surgery to help healing. It harnesses natural repair cells removed from your body fat to target problems affecting discs, joints, tendons, ligaments and muscles. The procedure takes around an hour and early results suggest an improvement for 75 per cent of suitable patients. This treatment contains concentrated blood plasma PRP/PRGF, as well as adipose-based pericytes harvested with Lipogems®. Theoretically AMPP® is superior in regeneration and healing. You may have AMPP® in conjunction with the treatment of other joints, the results of which have been very positive. Read Kathleen’s story who had Lipogems® treatment in her ankle. Her ankle is now pain free and she is pleased she could avoid surgery.

PRP therapy supports your body’s self-healing processes by using your own cells. Blood is mostly liquid (called plasma) but also contains solid component including red cells, white cells and platelets. The platelets are important for clotting blood but they also contain proteins called growth factors which are important in the healing of injuries.

With a higher concentration of growth factors than typically found in blood, PRP injections support the restoration of injured tissue and inhibit painful inflammatory processes.

This treatment is widely researched and supported in clinical papers. See our PRP evidence section.

Click to find out more about AMPP® or PRP treatments or make an appointment with one of our specialist orthopaedic consultants. Our expert team works as part of a collaborative partnership of Surgeons, Sports Medicine doctors and Physiotherapists to provide the perfect patient pathway to get you quickly on the road to recovery. Whether you require conventional treatment or if you are a candidate for these new regenerative treatments, you can be sure that will get the best advice from teaching hospital specialists.

Bone Marrow Aspirate Concentrate (BMAC) is a non-surgical, minimally invasive, regenerative treatment that harnesses the natural ability to heal the body through the assistance of biological growth factors. BMAC utilises the regenerative stem cells collected from bone marrow to aid in the acceleration of healing moderate to severe osteoarthritis and tendon injuries.

Bone marrow is extracted from the pelvis bone with a large needle and syringe under local anaesthetics. The harvested bone marrow is then processed into its separate components. The plasma, containing beneficial proteins, is filtered and condensed into a general fluid concentrate (GFC). Similarly, a fraction of the harvested marrow containing mesenchymal stem cells is concentrated into BMAC. Once processed, the BMAC and GFC are separately injected into the joint after sterile preparation and local anaesthetic is applied.

The injection offers:

Pain relief

Reduce swelling

Increase joint function

Improve condition of joint cartilage

Mr Nima Heidari

Consultant Foot, Ankle and Limb Reconstruction Surgeon

Mr Nicholas Savva

Consultant Orthopaedic Foot and Ankle and Trauma Surgeon

Mr Ansar Mahmood

Consultant Orthopaedic Surgeon


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Comparison of platelet-rich plasma and steroid injection in the treatment of plantar fasciitis


A Prospective Series of Patients with Chronic Achilles Tendinopathy

Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus


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