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Hand & Wrist Stem Cell and PRP Treatment and Therapy

Have you been told your only option for wrist, hand or finger pain is steroid injections or joint fusion surgery?
Minimally invasive regenerative alternatives offer pain relief and can help you get your lifestyle back on track

Stem cell therapy, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) treatment can provide relief from pain or a reduced range of motion for people suffering from hand, finger, thumb or wrist arthritis or other conditions of the hand.

Arthritis is the inflammation of one or more of your joints and the most common types are osteoarthritis and rheumatoid arthritis. Osteoarthritis is more common and is caused by the cartilage wearing away. Common symptoms are swelling, stiffness and decreased range of movement. Rheumatoid arthritis is a chronic disease which causes the joint lining to swell and leads to pain and stiffness in the joint. Rheumatoid arthritis often starts in the small joints of the hands and feet.

The hand and wrist have multiple small joints and therefore arthritis can occur in many areas. Thumb arthritis is very common and is wear of the cartilage at the base of the thumb joint, also known as the carpometacarpal joint.

Treatment initially involves anti-inflammatory medicines, splinting and corticosteroid injections.  If these options don’t work, joint fusions (which relieve pain but stop joint motion) or joint replacements can be performed.

Carpal tunnel syndrome causes pain, numbness, and tingling in the hand and arm. It occurs when one of the main nerves to the hand – the median nerve – is squeezed or compressed as it travels through the wrist.

Initially symptoms can be relieved through wearing a wrist splint or avoiding certain activities.

But if the pressure on the median nerve continues, it can lead to nerve damage and worsening symptoms. To prevent permanent damage, patients may be recommended surgery to take the pressure off the median nerve.

These conditions and other injuries to the wrist, hand and thumb can be treated with stem cell therapy, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) treatment which avoids the need for surgery and enables people to return to normal activities sooner.

Hand and wrist conditions which can be treated with AMPP® and PRP therapy include:

Hand arthritis

Thumb arthritis (basal joint arthritis/carpometacarpal arthritis)


Carpal/ulnar tunnel syndrome

Trigger finger

TFCC tear

The treatment

At The Regenerative Clinic we exclusively offer our patients AMPP® injections. A pioneering new treatment using your body’s own stem cells from a combination of Lipogems® and Platelet Rich Plasma Therapy to treat pain and inflammation. The minimally invasive procedure is a possible alternative to having an operation or can be used after surgery to help healing. It harnesses natural repair cells removed from your body fat to target problems affecting joints, tendons, ligaments and muscles. The procedure takes around an hour and early results suggest an improvement for 75 per cent of suitable patients.

This treatment contains concentrated blood plasma PRP/PRGF, as well as adipose-based pericytes harvested with Lipogems®. Theoretically AMPP® is superior in regeneration and healing. You may have AMPP® in conjunction with the treatment of other joints, the results of which have been very positive.

Read Francine’s story who had Lipogems® treatment in her shoulder. Her joints are now perfectly strong and her life has changed completely.

PRP therapy supports your body’s self-healing processes by using your own cells. Blood is mostly liquid (called plasma) but also contains solid component including red cells, white cells and platelets. The platelets are important for clotting blood but they also contain proteins called growth factors which are important in the healing of injuries.

With a higher concentration of growth factors than typically found in blood, PRP injections support the restoration of injured tissue and inhibit painful inflammatory processes.

This treatment is widely researched and supported in clinical papers. See our PRP evidence section.

Click to find out more about AMPP® or PRP treatments or make an appointment with one of our specialist orthopaedic consultants. Our expert team works as part of a collaborative partnership of Surgeons, Sports Medicine doctors and Physiotherapists to provide the perfect patient pathway to get you quickly on the road to recovery. Whether you require conventional treatment or if you are a candidate for these new regenerative treatments, you can be sure that will get the best advice from teaching hospital specialists.

Bone Marrow Aspirate Concentrate (BMAC) is a non-surgical, minimally invasive, regenerative treatment that harnesses the natural ability to heal the body through the assistance of biological growth factors. BMAC utilises the regenerative stem cells collected from bone marrow to aid in the acceleration of healing moderate to severe osteoarthritis and tendon injuries.

Bone marrow is extracted from the pelvis bone with a large needle and syringe under local anaesthetics. The harvested bone marrow is then processed into its separate components. The plasma, containing beneficial proteins, is filtered and condensed into a general fluid concentrate (GFC). Similarly, a fraction of the harvested marrow containing mesenchymal stem cells is concentrated into BMAC. Once processed, the BMAC and GFC are separately injected into the joint after sterile preparation and local anaesthetic is applied.

The injection offers:

  • Pain relief
  • Reduce swelling
  • Increase joint function
  • Improve condition of joint cartilage

Mr Matthew Smith

Consultant Orthopaedic Surgeon - FRCS (Tr & Orth)


AMPP® injections into both knees, hips, shoulders, elbows and ankles


Lipogems® injection into both knees and hands


Lipogems® injection into right shoulder, right hip, right knee, sacroiliac joints, shin and fingers.
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