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Knee Stromal Cell ‘Growth Factors’ and PRP Treatment and Therapy

The knee is the largest joint in the body and therefore can suffer from a range of injuries both traumatic and inflammatory.

Knee pain and injuries can be treated by stromal cell therapy, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) treatment.

The most common knee injuries include fractures, dislocations and sprains and tears of soft tissues such as ligaments. Knee pain can also be caused by arthritis. Osteoarthritis which is also called degenerative arthritis, is the most common type of arthritis and occurs when the cartilage in the knee deteriorates with use and age. This wear and tear can be medial (inside of the knee) or lateral (outside of the knee).

Treatment for knee conditions such as osteoarthritis is usually initially aimed at relieving the pain and involves anti-inflammatory medicines and physiotherapy. This may be followed by a series of corticosteroid injections. The next step may be an arthroscopy and if the condition continues you may require knee replacement surgery.

Stromal cell ‘growth factors’, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) therapy can delay or avoid the need for knee surgery. The treatments are minimally invasive, can decrease inflammation, stop the progression of arthritic damage and repair joint cartilage. The recovery time is also much shorter than with surgery.

Knee conditions which can be treated with AMPP® and PRP therapy include:

Knee pain
Knee osteoarthritis (medial and lateral)
Knee bursitis
Bakers cyst
Patellar tendinopathy
Hamstring tendinopathy
Alternatives to Knee Replacement

Patellofemoral syndrome (runner’s knee)
Meniscus tears
Traumatic ligament injuries
Knee Sprains and Strains
Sport injuries
Degenerative conditions

The treatment

At The Regenerative Clinic we exclusively offer our patients AMPP® injections. A pioneering new treatment using your body’s own stromal cell ‘growth factors’ from a combination of Lipogems® and Platelet Rich Plasma Therapy to treat pain and inflammation. The minimally invasive procedure is a possible alternative to having an operation or can be used after surgery to help healing. It harnesses natural repair cells removed from your body fat to target problems affecting joints, tendons, ligaments and muscles. The procedure takes around an hour and early results suggest an improvement for 75 per cent of suitable patients.

This treatment contains concentrated blood plasma PRP, as well as adipose-based pericytes harvested with Lipogems®. Theoretically AMPP® is superior in regeneration and healing. You may have AMPP® in conjunction with the treatment of other joints, the results of which have been very positive.

PRP Therapy supports your body’s self-healing processes by using your own cells. Blood is mostly liquid (called plasma) but also contains solid component including red cells, white cells and platelets. The platelets are important for clotting blood but they also contain proteins called growth factors which are important in the healing of injuries.

With a higher concentration of growth factors than typically found in blood, PRP injections support the restoration of injured tissue and inhibit painful inflammatory processes.

This treatment is widely researched and supported in clinical papers. See our PRP evidence section.

Click to find out more about AMPP® or PRP treatments or make an appointment with one of our specialist orthopaedic consultants.

Our expert team works as part of a collaborative partnership of Surgeons, Sports Medicine doctors and Physiotherapists to provide the perfect patient pathway to get you quickly on the road to recovery. Whether you require conventional treatment or if you are a candidate for these new regenerative treatments, you can be sure that will get the best advice from teaching hospital specialists

Bone Marrow Aspirate Concentrate (BMAC) is a non-surgical, minimally invasive, regenerative treatment that harnesses the natural ability to heal the body through the assistance of biological growth factors. BMAC utilises the regenerative stem cells collected from bone marrow to aid in the acceleration of healing moderate to severe osteoarthritis and tendon injuries.

Bone marrow is extracted from the pelvis bone with a large needle and syringe under local anaesthetics. The harvested bone marrow is then processed into its separate components. The plasma, containing beneficial proteins, is filtered and condensed into a general fluid concentrate (GFC). Similarly, a fraction of the harvested marrow containing mesenchymal stem cells is concentrated into BMAC. Once processed, the BMAC and GFC are separately injected into the joint after sterile preparation and local anaesthetic is applied.

The injection offers:

Pain relief
Reduce swelling
Increase joint function
Improve condition of joint cartilage

Professor Adrian Wilson

Consultant Knee Surgeon (Professor)

Mr Sam Heaton

Consultant Knee and Hip Orthopaedic Surgeon

Mr Amit Kumar

Consultant Orthopaedic Surgeon

Mr Rohit Jain

Consultant Orthopaedic Hip, Knee

Mr Ed Britton

Consultant Orthopaedic Surgeon


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